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1

Liposomal drug delivery systems: From concept to clinical applications

Allen, Theresa M., Cullis, Pieter R.

Journal:

Advanced Drug Delivery Reviews

Year:

2013

Language:

english

File:

PDF, 344 KB

english, 2013

2

Lipid Nanoparticle Technology for Clinical Translation of siRNA Therapeutics

Kulkarni, Jayesh A., Witzigmann, Dominik, Chen, Sam, Cullis, Pieter R., van der Meel, Roy

Journal:

Accounts of Chemical Research

Year:

2019

Language:

english

File:

PDF, 3.65 MB

english, 2019

3

Microfluidic Mixing: A General Method for Encapsulating Macromolecules in Lipid Nanoparticle Systems

Leung, Alex K. K., Tam, Yuen Yi C., Chen, Sam, Hafez, Ismail M., Cullis, Pieter R.

Journal:

Journal of Physical Chemistry B

Year:

2015

Language:

english

File:

PDF, 2.23 MB

english, 2015

4

Influence of cationic lipid composition on uptake and intracellular processing of lipid nanoparticle formulations of siRNA

Lin, Paulo J.C., Tam, Yuen Yi C., Hafez, Ismail, Sandhu, Ammen, Chen, Sam, Ciufolini, Marco A., Nabi, Ivan R., Cullis, Pieter R.

Journal:

Nanomedicine: Nanotechnology, Biology and Medicine

Year:

2013

Language:

english

File:

PDF, 2.18 MB

english, 2013

5

Production of limit size nanoliposomal systems with potential utility as ultra-small drug delivery agents

Zhigaltsev, Igor V., Tam, Ying K., Leung, Alex K. K., Cullis, Pieter R.

Journal:

Journal of Liposome Research

Year:

2015

Language:

english

File:

PDF, 374 KB

english, 2015

6

The Biomolecular Corona of Lipid Nanoparticles for Gene Therapy

Francia, Valentina, Schiffelers, Raymond M., Cullis, Pieter R, Witzigmann, Dominik

Journal:

Bioconjugate Chemistry

Year:

2020

File:

PDF, 18.64 MB

2020

7

Design of lipid nanoparticles for in vitro and in vivo delivery of plasmid DNA

Kulkarni, Jayesh A., Myhre, Johnathan Layne, Chen, Sam, Tam, Yuen Yi C., Danescu, Adrian, Richman, Joy M., Cullis, Pieter R.

Journal:

Nanomedicine: Nanotechnology, Biology and Medicine

Year:

2017

Language:

english

File:

PDF, 2.20 MB

english, 2017

8

Formation and Morphology of Lipid Nanoparticles Containing Ionizable Cationic Lipids and siRNA

Kulkarni, Jayesh A., Darjuan, Maria M., Mercer, Joanne E., Chen, Sam, van der Meel, Roy, Thewalt, Jenifer L., Tam, Yuen Yi C., Cullis, Pieter R.

Journal:

Year:

2018

Language:

english

File:

PDF, 14.69 MB

english, 2018

9

State-of-the-Art Design and Rapid-Mixing Production Techniques of Lipid Nanoparticles for Nucleic Acid Delivery

Evers, Martijn J. W., Kulkarni, Jayesh A., van der Meel, Roy, Cullis, Pieter R., Vader, Pieter, Schiffelers, Raymond M.

Journal:

Year:

2018

Language:

english

File:

PDF, 1.63 MB

english, 2018

10

Polymorphic phase behavior of alpha-tocopherol hemisuccinate

Lawrence T. Boni, Walter R. Perkins, Sharma R. Minchey, Lois E. Bolcsak, Sol M. Gruner, Pieter R. Cullis, Michael J. Hope, Andrew S. Janoff

Journal:

Chemistry and Physics of Lipids

Year:

1990

Language:

english

File:

PDF, 1.21 MB

english, 1990

11

Studies on the myelosuppressive activity of doxorubicin entrapped in liposomes

Marcel B. Bally, Rajiv Nayar, D. Masin, Pieter R. Cullis, Lawrence D. Mayer

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1990

Language:

english

File:

PDF, 916 KB

english, 1990

12

Intratumor distribution of doxorubicin following i.v. administration of drug encapsulated in egg phosphatidylcholine/cholesterol liposomes

T. O. Harasym, Pieter R. Cullis, Marcel B. Bally

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1997

Language:

english

File:

PDF, 482 KB

english, 1997

13

Interactions of liposomes and lipid-based carrier systems with blood proteins: Relation to clearance behaviour in vivo

Sean C Semple, Arcadio Chonn, Pieter R Cullis

Journal:

Advanced Drug Delivery Reviews

Year:

1998

Language:

english

File:

PDF, 531 KB

english, 1998

14

Characterization of liposomal systems containing doxorubicin entrapped in response to pH gradients

Lawrence D. Mayer, Linda C.L. Tai, Marcel B. Bally, George N. Mitilenes, Richard S. Ginsberg, Pieter R. Cullis

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1990

Language:

english

File:

PDF, 802 KB

english, 1990

15

Efficient encapsulation of antisense oligonucleotides in lipid vesicles using ionizable aminolipids: formation of novel small multilamellar vesicle structures

Sean C. Semple, Sandra K. Klimuk, Troy O. Harasym, Nancy Dos Santos, Steven M. Ansell, Kim F. Wong, Norbert Maurer, Holger Stark, Pieter R. Cullis, Michael J. Hope, Peter Scherrer

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2001

Language:

english

File:

PDF, 940 KB

english, 2001

16

[New Comprehensive Biochemistry] Biochemistry of Lipids, Lipoproteins and Membranes Volume 31 || Physical properties and functional roles of lipids in membranes

Cullis, Pieter R.

Year:

1996

Language:

english

File:

PDF, 2.08 MB

english, 1996

17

Developments in liposomal drug delivery systems

Maurer, Norbert, Fenske, David B, Cullis, Pieter R

Journal:

Expert Opinion on Biological Therapy

Year:

2001

Language:

english

File:

PDF, 1.46 MB

english, 2001

18

The Cellular Mechanisms of Neuronal Swelling Underlying Cytotoxic Edema

Rungta, Ravi L., Choi, Hyun B., Tyson, John R., Malik, Aqsa, Dissing-Olesen, Lasse, Lin, Paulo J.C., Cain, Stuart M., Cullis, Pieter R., Snutch, Terrance P., MacVicar, Brian A.

Journal:

Year:

2015

Language:

english

File:

PDF, 3.33 MB

english, 2015

19

Systemic Gene Silencing in Primary T Lymphocytes Using Targeted Lipid Nanoparticles

Ramishetti, Srinivas, Kedmi, Ranit, Goldsmith, Meir, Leonard, Fransisca, Sprague, Andrew G., Godin, Biana, Gozin, Michael, Cullis, Pieter R., Dykxhoorn, Derek M., Peer, Dan

Journal:

Year:

2015

Language:

english

File:

PDF, 4.75 MB

english, 2015

20

Controlling the Drug Delivery Attributes of Lipid-Based Drug Formulations

Bally, Marcel B., Lim, Howard, Cullis, Pieter R., Mayer, Lawrence D.

Journal:

Journal of Liposome Research

Year:

1998

Language:

english

File:

PDF, 2.43 MB

english, 1998

21

614. Microfluidic Manufacture of RNA-Lipid Nanoparticles Leads to Highly Efficient Delivery of Potent Nucleic Acid Therapeutics for Controlling Gene Expression

Tharmarajah, Grace, Ouellet, Eric, Seira, Oscar, Liu, Jie, Thomas, Anitha, Leaver, Timothy, Wild, Andre, Li, Yuping, Wang, Yu Tian, Tetzlaff, Wolfram, Hansen, Carl, Cullis, Pieter, Taylor, James R., R

Journal:

Molecular Therapy

Year:

2016

Language:

english

File:

PDF, 334 KB

english, 2016

22

Lipid-Based DNA Therapeutics – Hallmarks of Non-Viral Gene Delivery

Buck, Jonas, Grossen, Philip, Cullis, Pieter R, Huwyler, Jörg, Witzigmann, Dominik

Journal:

Year:

2019

Language:

english

File:

PDF, 1.14 MB

english, 2019

23

Use of a lipid nanoparticle system as a Trojan horse in delivery of gold nanoparticles to human breast cancer cells for improved outcomes in radiation therapy

Bromma, Kyle, Rieck, Kristy, Kulkarni, Jayesh, O’Sullivan, Connor, Sung, Wonmo, Cullis, Pieter, Schuemann, Jan, Chithrani, Devika B.

Journal:

Cancer Nanotechnology

Year:

2019

File:

PDF, 3.58 MB

2019

24

Phospholipid‐Free Small Unilamellar Vesicles for Drug Targeting to Cells in the Liver

Zhang, Wunan, Böttger, Roland, Qin, Zhu, Kulkarni, Jayesh A., Vogler, Julian, Cullis, Pieter R., Li, Shyh‐Dar

Journal:

Year:

2019

Language:

english

File:

PDF, 2.53 MB

english, 2019

25

Value-based healthcare delivery through metabolomics-based personalized health platform

Anwar, Mohammad A., Barrera-Machuca, Aldo A., Calderon, Nadya, Wang, Windy, Tausan, Daniel, Vayali, Thara, Wishart, David, Cullis, Pieter, Fraser, Robert

Journal:

Healthcare Management Forum

Year:

2020

Language:

english

File:

PDF, 524 KB

english, 2020

26

Spontaneous, solvent-free entrapment of siRNA within lipid nanoparticles

Kulkarni, Jayesh A, Thomson, Sarah B, Zaifman, Josh, Leung, Jerry, Tam, Yuen Yi C, Cullis, Pieter R, Petkau, Terri L, Leavitt, Blair R

Journal:

Year:

2020

File:

PDF, 1.93 MB

2020

27

Development of high-concentration lipoplexes for in vivo gene function studies in vertebrate embryos

Poongodi Geetha-Loganathan, Suresh Nimmagadda, Ismail Hafez, Katherine Fu, Pieter R. Cullis, Joy M. Richman

Journal:

Developmental Dynamics

Year:

2011

Language:

english

File:

PDF, 7.96 MB

english, 2011

28

Freeze-fracture of lipids and model membrane systems

Dr. Michael J. Hope, Kim F. Wong, Pieter R. Cullis

Journal:

Microscopy Research and Technique

Year:

1989

Language:

english

File:

PDF, 1.77 MB

english, 1989

29

The combination of stabilized plasmid lipid particles and lipid nanoparticle encapsulated CpG containing oligodeoxynucleotides as a systemic genetic vaccine

Kaley D. Wilson, Susan D. de Jong, Mikameh Kazem, Ryan Lall, Michael J. Hope, Pieter R. Cullis, Ying K. Tam

Journal:

The Journal of Gene Medicine

Year:

2009

Language:

english

File:

PDF, 262 KB

english, 2009

30

Optimization and characterization of a sphingomyelin/cholesterol liposome formulation of vinorelbine with promising antitumor activity

Sean C. Semple, Robert Leone, Jinfang Wang, Esther C. Leng, Sandra K. Klimuk, Merete L. Eisenhardt, Zuan-Ning Yuan, Katarina Edwards, Norbert Maurer, Michael J. Hope, Pieter R. Cullis, Quet-Fah Ahkong

Journal:

Journal of Pharmaceutical Sciences

Year:

2005

Language:

english

File:

PDF, 233 KB

english, 2005

31

Chromatographic analysis and pharmacokinetics of liposome-encapsulated doxorubicin in non-small-cell lung cancer patients

Leanne Embree, Karen A. Gelmon, Andreas Lohr, Lawrence D. Mayer, Andrew J. Coldman, Pieter R. Cullis, Waldemar Palaitis, Frank Pilkiewicz, Norma J. Hudon, Jean R. Heggie, James H. Goldie

Journal:

Journal of Pharmaceutical Sciences

Year:

1993

Language:

english

File:

PDF, 1024 KB

english, 1993

32

Techniques for encapsulating bioactive agents into liposomes

Lawrence D. Mayer, Marcel B. Bally, Michael J. Hope, Pieter R. Cullis

Journal:

Chemistry and Physics of Lipids

Year:

1986

Language:

english

File:

PDF, 706 KB

english, 1986

33

Dopamine accumulation in large unilamellar vesicle systems induced by transmembrane ion gradients

Marcel B. Bally, Lawrence D. Mayer, Helen Loughrey, Tom Redelmeier, Thomas D. Madden, Kim Wong, P.Richard Harrigan, Michael J. Hope, Pieter R. Cullis

Journal:

Chemistry and Physics of Lipids

Year:

1988

Language:

english

File:

PDF, 806 KB

english, 1988

34

The accumulation of drugs within large unilamellar vesicles exhibiting a proton gradient: a survey

Thomas D. Madden, P.Richard Harrigan, Linda C.L. Tai, Marcel B. Bally, Lawrence D. Mayer, Tom E. Redelmeier, Helen C. Loughrey, Colin P.S. Tilcock, Lawrence W. Reinish, Pieter R. Cullis

Journal:

Chemistry and Physics of Lipids

Year:

1990

Language:

english

File:

PDF, 601 KB

english, 1990

35

Liposomal Gd-DTPA: Effect of encapsulation on enhancement of hepatoma model by MRI

Evan C. Unger, Peter MacDougall, Pieter Cullis, Colin Tilcock

Journal:

Magnetic Resonance Imaging

Year:

1989

Language:

english

File:

PDF, 3.52 MB

english, 1989

36

Recent advances in liposomal drug-delivery systems

Arcadio Chonn, Pieter R Cullis

Journal:

Current Opinion in Biotechnology

Year:

1995

Language:

english

File:

PDF, 970 KB

english, 1995

37

Calcium enhances the transfection potency of stabilized plasmid–lipid particles

Ammen P. Sandhu, Angela M.I. Lam, David B. Fenske, Lorne R. Palmer, Michael Johnston, Pieter R. Cullis

Journal:

Analytical Biochemistry

Year:

2005

Language:

english

File:

PDF, 1009 KB

english, 2005

38

Investigation of factors responsible for cell line cytoplasmic expression differences

Jonathan D Finn, Tabitha Wong, Pieter R Cullis

Journal:

BMC Molecular Biology

Year:

2005

Language:

english

File:

PDF, 665 KB

english, 2005

39

Encapsulation in liposomal nanoparticles enhances the immunostimulatory, adjuvant and anti-tumor activity of subcutaneously administered CpG ODN

Susan de Jong, Ghania Chikh, Laura Sekirov, Sam Raney, Sean Semple, Sandra Klimuk, Ning Yuan, Micheal Hope, Pieter Cullis, Ying Tam

Journal:

Cancer Immunology, Immunotherapy

Year:

2007

Language:

english

File:

PDF, 427 KB

english, 2007

40

Vincristine-induced dermal toxicity is significantly reduced when the drug is given in liposomes

N. L. Boman, Victor A. Tron, Marcel B. Bally, Pieter R. Cullis

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1996

Language:

english

File:

PDF, 977 KB

english, 1996

41

Binding and Uptake of RGD-Containing Ligands to Cellularαvβ3Integrins

Sonya Cressman, Ying Sun, E. Jane Maxwell, Ning Fang, David D. Y. Chen, Pieter R. Cullis

Journal:

International Journal of Peptide Research and Therapeutics

Year:

2009

Language:

english

File:

PDF, 421 KB

english, 2009

42

Method for rapid separation of liposome-associated doxorubicin from free doxorubicin in plasma

Robert L. Thies, D.Wayne Cowens, Pieter R. Cullis, Marcel B. Bally, Lawrence D. Mayer

Journal:

Analytical Biochemistry

Year:

1990

Language:

english

File:

PDF, 814 KB

english, 1990

43

Lipid polymorphism and the roles of lipids in membranes

Pieter R. Cullis, Michael J. Hope, Colin P.S. Tilcock

Journal:

Chemistry and Physics of Lipids

Year:

1986

Language:

english

File:

PDF, 1015 KB

english, 1986

44

10.1038/32309

Schmid, Sandra L., Cullis, Pieter R.

Journal:

Year:

1998

Language:

english

File:

PDF, 206 KB

english, 1998

45

Lipid nanoparticle siRNA systems for silencing the androgen receptor in human prostate cancer in vivo

Justin B. Lee, Kaixin Zhang, Yuen Yi C. Tam, Ying K. Tam, Nathan M. Belliveau, Vanessa Y.C. Sung, Paulo J.C. Lin, Eric LeBlanc, Marco A. Ciufolini, Paul S. Rennie, Pieter R. Cullis

Journal:

International Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 753 KB

english, 2012

46

Liposome-encapsulated vincristine, vinblastine and vinorelbine: A comparative study of drug loading and retention

Igor V. Zhigaltsev, Norbert Maurer, Quet-Fah Akhong, Robert Leone, Esther Leng, Jinfang Wang, Sean C. Semple, Pieter R. Cullis

Journal:

Journal of Controlled Release

Year:

2005

Language:

english

File:

PDF, 164 KB

english, 2005

47

Formation of drug–arylsulfonate complexes inside liposomes: A novel approach to improve drug retention

Igor V. Zhigaltsev, Norbert Maurer, Katarina Edwards, Göran Karlsson, Pieter R. Cullis

Journal:

Journal of Controlled Release

Year:

2006

Language:

english

File:

PDF, 509 KB

english, 2006

48

An immune response to ovalbumin covalently coupled to liposomes is prevented when the liposomes used contain doxorubicin

Paul G Tardi, Erik N Swartz, Troy O Harasym, Pieter R Cullis, Marcel B Bally

Journal:

Journal of Immunological Methods

Year:

1997

Language:

english

File:

PDF, 272 KB

english, 1997

49

Roles of lipid polymorphism in intracellular delivery

Ismail M. Hafez, Pieter R. Cullis

Journal:

Advanced Drug Delivery Reviews

Year:

2001

Language:

english

File:

PDF, 494 KB

english, 2001

50

Recent advances in liposome technologies and their applications for systemic gene delivery

Arcadio Chonn, Pieter R Cullis

Journal:

Advanced Drug Delivery Reviews

Year:

1998

Language:

english

File:

PDF, 785 KB

english, 1998

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